ASEQ: fast allele-specific studies from next-generation sequencing data
نویسندگان
چکیده
منابع مشابه
Allele-specific copy number profiling by next-generation DNA sequencing
The progression and clonal development of tumors often involve amplifications and deletions of genomic DNA. Estimation of allele-specific copy number, which quantifies the number of copies of each allele at each variant loci rather than the total number of chromosome copies, is an important step in the characterization of tumor genomes and the inference of their clonal history. We describe a ne...
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ژورنال
عنوان ژورنال: BMC Medical Genomics
سال: 2015
ISSN: 1755-8794
DOI: 10.1186/s12920-015-0084-2